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Over the last 3 years, the Government's technology foresight programme has sought to identify opportunities in markets likely to emerge during the next 10-20 years, and its results now inform funding decisions for much of the UK's science and engineering base. However technology moves fast, and such exercises must remain alert to the latest developments - especially where these affect many areas of science and technology. One such "generic technology" may be nanotechnology, or the technology of the very small, where a human hair would appear as large as a building in a "nanoscale" world.